blue #
= weekly pop chart peak
| 1 | Never | Mar 2004 |  |
| Keyshia Cole Featuring Eve |
| 2 | I Changed My Mind | Nov 2004 | |
| 3 | (I Just Want It) To Be Over | May 2005 | |
| Keyshia Cole Featuring Alicia Keys |
| 4 | I Should Have Cheated | Dec 2005 | |
| 5 | Love | Apr 2006 | |
| 6 | (When You Gonna) Give It Up To Me | 1 | Aug 2006 | |
| Sean Paul Featuring Keyshia Cole |
| 7 | Last Night | 7 | Apr 2007 | |
| Diddy Featuring Keyshia Cole |
| 8 | Dreamin' | Jun 2007 | |
| Young Jeezy Featuring Keyshia Cole |
| 9 | Let It Go | 20 | Oct 2007 | |
| Keyshia Cole Featuring Missy Elliott And Lil Kim |
| 10 | Shoulda Let You Go | Dec 2007 | |
| Keyshia Cole Introducing Amina |
| 11 | I Remember | Feb 2008 | |
| 12 | Boyfriend/Girlfriend | May 2008 | |
| C-Side Featuring Keyshia Cole |
| 13 | Game's Pain | Jul 2008 | |
| The Game Featuring Keyshia Cole |
| 14 | Heaven Sent | Jul 2008 | |
| 15 | I've Changed | Aug 2008 | |
| Jaheim Featuring Keyshia Cole |
| 16 | Playa Cardz Right | Dec 2008 | |
| Keyshia Cole Featuring 2Pac |
| 17 | You Complete Me | Mar 2009 | |
| 18 | Where This Love Could End Up | Jul 2009 | |
| 19 | Beautiful Music | Aug 2009 | |
| 20 | Trust | Aug 2009 | |
| Keyshia Cole Featuring Monica |
| 21 | Have Yourself A Merry Little Christmas | Dec 2009 | |
| 22 | Get Your Money Up | Feb 2010 | |
| Keri Hilson Featuring Keyshia Cole & Trina |
| 23 | I Ain't Thru | Jan 2011 | |
| Keyshia Cole Featuring Nicki Minaj |
| 24 | Long Way Down | Jan 2011 | |
| 25 | Take Me Away | Mar 2011 | |
| 26 | Enough Of No Love | Sep 2012 | |
| Keyshia Cole Featuring Lil Wayne |
| 27 | Trust And Believe | Feb 2013 | |
| 28 | I Choose You | Oct 2013 | |
| 29 | Next Time (Won't Give My Heart Away) | May 2014 | |
| 30 | She | Aug 2014 | |